easymode training collection

To achieve general networks, we compiled a large and diverse training data collection using private and public data contributions. The table below lists the current data sources.

The training collection currently contains 2292 tomograms, from 49 unique data sources, spanning 22 species, a pixel size range of 0.68 Å to 4.27 Å, and many sample types including purified proteins, cellular lysates, whole cells, fib-milled cultured cells, and high-pressure frozen, lifted-out tissue lamellas.

We're very grateful to the many people who shared their data via EMPIAR and the CryoET Data Portal!

ID Contributor / source Sample type N (annotated) Pixel size (Å)
001_HELA Mart Last milled H. sapiens (HeLa) 60 (59) 1.51
002_U2OS Mart Last milled H. sapiens (U2OS) 40 (26) 2.15
003_HSPERM Tom Dendooven milled H. sapiens (spermatozoa) 56 (41) 1.50
004_* * * 23 (20) 1.68
005_FIBRO Tom Hale milled H. sapiens (fibroblasts) 52 (47) 1.33
006_* * * 20 (16) 1.69
007_APOF EMPIAR-10491 purified apoferritin 37 (18) 0.79
008_HIV EMPIAR-10164 purified HIV particles 10 (4) 0.68
009_SCEREV Sebastian Tacke, Elisa Lisicki,
Tatjana Taubitz, Stefan Raunser
milled (hpf, pfib) S. cerevisiae 64 (51) 1.56
010_RIBO EMPIAR-11111 purified E. coli 70S ribosomes 25 (19) 1.07
011_CHLO EMPIAR-12612 milled S. oleracea chloroplasts 23 (18) 3.52
012_CHLAMY EMPIAR-11830 milled C. reinhardtii 52 (50) 1.96
013_DIAT EMPIAR-11747 milled T. pseudonana 7 (1) 1.07
014_CILIA EMPIAR-11078 milled C. reinhardtii ciliary base 23 (19) 3.42
015_MMVOLTA CDPDS-10452 whole M. mycoides cells 15 (15) 1.53
016_PHANTOM CDPDS-10440, CDPDS-10445 E. coli lysate with added proteins 19 (17) 1.53
017_MYCP EMPIAR-10499 whole M. pneunomiae cells 65 (27) 1.70
018_ECM EMPIAR-11897 lift-out H. sapiens (extracellular matrix) 39 (24) 2.14
019_ECOLI EMPIAR-12413 milled E. coli 44 (19) 1.90
020_* * * 30 (25) 2.13
021_* * * 8 (7) 3.02
022_SCOV EMPIAR-10493 purified SARS-CoV-2 virions 20 (12) 1.53
023_SPORE EMPIAR-12176 milled E. intestinalis 24 (11) 2.06
024_* * * 17 (6) 1.96
025_RPE EMPIAR-10989 cellular periphery H. sapiens (RPE1) 3 (3) 3.45
026_EHV EMPIAR-11896 Emiliania huxleyi virus 201 40 (10) 2.08
027_NUCFT Forson Gao milled S. cerevisiae nuclei 21 (15) 1.51
028_ROOF CDPDS-10434 cellular periphery H. sapiens (HEK293) 20 (19) 2.17
029_TKIV EMPIAR-11058 milled T. kivui 17 (7) 3.52
030_LDN Mart Last cellular periphery H. sapiens (U2OS) 26 (7) 2.74
031_MITO Mart Last milled H. sapiens (HeLa, mitochondria) 63 (59) 1.34
032_* * * 40 (24) 1.63
033_NPC EMPIAR-11830 (same source as 012_CHLAMY) milled C. reinhardtii (nuclear envelope) 36 (36) 1.96
034_DICTYO EMPIAR-11845 milled D. discoideum 152 (68) 2.18
035_GEM EMPIAR-11561 milled H. sapiens (HeLa, mitochondria) 15 (14) 3.43
036_MACRO EMPIAR-12457 milled H. sapiens (macrophages) 39 (21) 2.41
037_MESWT EMPIAR-12460 milled M. musculus (embryonic stem cell) 159 (26) 2.68
038_POMBE EMPIAR-10988 milled S. pombe 9 (6) 3.37
039_JUMBO EMPIAR-11198 milled E. amylovora + RAY phage 32 (4) 4.27
040_SLO CDPDS-10004 milled (hpf, pfib) C. elegans 100 (24) 1.50
041_RPEM Cong Yu (MRC LMB) milled H. sapiens (RPE1) 17 (7) 1.57
042_NPCSC EMPIAR-10466 milled S. cerevisiae 177 (0) 3.45
043_DICTY2 EMPIAR-11899 (to be included after validation) milled D. discoideum 0 (0) 1.22
044_JURKAT Mart Last milled H. sapiens (Jurkat) 0 (0) 1.97
045_NPHL * * 231 (0) 1.56
046_ROOF2 CDPDS-10431 cellular preiphery H. sapiens (HEK293) 87 (0) 2.17
047_ECPP7 CDPDS-10455 E. coli + PP7 virus-like particles 30 (0) 1.50
048_ELSO CDPDS-10444 purified human endo-/lysosomes 30 (0) 1.54
049_* * *
050_* * *